PEI Yang-yang,SONG Qing,LI Peng.Research Progress of Biomimetic Micro/Nano-structured Antibacterial Surfaces[J],48(7):200-210 |
Research Progress of Biomimetic Micro/Nano-structured Antibacterial Surfaces |
Received:November 15, 2018 Revised:July 20, 2019 |
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DOI:10.16490/j.cnki.issn.1001-3660.2019.07.022 |
KeyWord:antibacterial surfaces biomimetic materials micro/nano-structured surfaces surface modification bacterial adhesion biofilm antibacterial mechanisms |
Author | Institution |
PEI Yang-yang |
Institute of Flexible Electronics, Northwestern Polytechnical University, Xi'an , China |
SONG Qing |
Institute of Flexible Electronics, Northwestern Polytechnical University, Xi'an , China |
LI Peng |
Institute of Flexible Electronics, Northwestern Polytechnical University, Xi'an , China |
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Abstract: |
The preparation of materials with antimicrobial properties by surface modification technology is one of the research hotspots in the field of antimicrobial materials in recent years. This review briefly introduced the characteristics and antimicrobial effects of natural antimicrobial micro/nano-structure, and summarized the research progress of simulating micro/nano-structures of cicada and dragonfly wing, moth eyes, and gecko skin by using different techniques from the aspects of inspiration sources, substrate materials, fabrication methods, surface characteristics and structures, and antimicrobial efficiencies. The effect of surface morphology and roughness of micro/nanostructure on the antimicrobial efficiency was discussed. It was found that the surface structures with multi-layered, closely spaced, and sharp ended nanopillars had strong antimicrobial activities against both Gram-positive and Gram-negative bacteria. Recent studies showed that these natural antimicrobial surfaces interacted with bacteria and destroyed cell wall/membranes, resulting in bacterial death. The antibacterial mechanism of the micro/nano-structured surfaces is physico-mechanical, and therefore the surfaces prevent the occurrence of bacterial resistance. This review provided the theoretical basis for the future development of biomimetic micro/nano-structured antibacterial surfaces, and pointed out the future research directions in this promising field. |
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